Abstract
There have been very few reports about secondary amyloidosis of the temporomandibular joint affected by rheumatoid arthritis. We presented a case of secondary amyloidosis of temporomandibular joint of a 68-year-old man with severe rheumatoid arthritis. Total TMJ replacement was performed bilaterally and TMJ specimens were harvested for examination. Deposition of amyloid was detected histologically in TMJ with Congo-red stain. Immunohistochemical observation also revealed CD68 positive cells in bone marrow. It was suggested that macrophage related to secondary amyloidosis in rheumatoid artritis of TMJ. Furthermore investigations were required to clear the mechanisum of temporomandibular joint rheumatoid arthritis.