Abstract
The endoscopic features of malignant lymphoma of the small and large intestines were reviewed. The most frequent histologic type is diffuse large B-cell lymphoma (DLBCL), and follicular lymphoma and T-cell lymphomas are more frequent in intestinal cases than in gastric cases. Endoscopically, intestinal lymphomas are classified as polypoid, ulcerative (including stricturing, non-stricturing and aneurysmal sub-forms), multiple lymphomatous polyposis (MLP), diffuse, or mixed types. A significant correlation is observed between these endoscopic and histologic types ; most cases of ulcerative type are histologically DLBCL, while the majority of tumors of polypoid type are comprised of MALT lymphoma or DLBCL. In MLP type, follicular lymphoma and mantle cell lymphoma are frequent, while diffuse type is characteristic of T-cell lymphomas and immunoproliferative small intestinal disease. In addition to conventional esophagogastroduodenoscopy and colonoscopy, double-balloon endoscopy is useful for the detection and accurate diagnosis of intestinal malignant lymphoma.
