Abstract
Human intestinal spirochetosis (HIS) is considered a zoonotic agent. HIS is a common condition in the Western and developing countries, especially in homosexual men and HIV infected patients. HIS have been implicated in the manifestation of bowel symptoms such as purulent discharge, diarrhea, and rectal bleeding. Histopathologicaly, it is characterized by being basophilic and flocculent colonies that adhere to the epithelial surface of the large intestine. We report two cases of intestinal spirochetosis caused by B. aalborgi, which was complicated amebic colitis in Japan.