Abstract
A 69-year-old female was admitted due to bloody stool in August, 2005. Colonoscopic examination showed the lesions like a blood blisters, and were surrounded by vascular ectasia. On pathology immunoglobulin light chain amyloidosis (AL) was diagnosed. She was treated for amyloidosis, but 7 months later, she again developed abdominal pain and had bloody stool. Colonoscopic examination showed ischemic colitis with a broad ulcerative lesion and mucosal abrasion in the sigmoid colon. On pathology amyloid deposits were noted in the wall of a submucosal vessel. The amyloid deposits were localized in the large intestine. This patient likely had localized primary AL-type amyloidosis. The patient's symptoms quickly improved with intravenous hypernutrition.