GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
A CASE OF AL-TYPE AMYLOIDOSIS OF THE COLON FOLLOWED-UP BY ENDOSCOPIC OBSERVATION
Shigetoshi URABE, Masaki YAMAKAWA, Shoko IMAMURA, Takuji YAMAO, Jyunji IRIE, Youhei MIZUTA, Shigeru KOHNO
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JOURNAL OPEN ACCESS

2009 Volume 51 Issue 4 Pages 1148-1158

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Abstract
A 69-year-old female was admitted due to bloody stool in August, 2005. Colonoscopic examination showed the lesions like a blood blisters, and were surrounded by vascular ectasia. On pathology immunoglobulin light chain amyloidosis (AL) was diagnosed. She was treated for amyloidosis, but 7 months later, she again developed abdominal pain and had bloody stool. Colonoscopic examination showed ischemic colitis with a broad ulcerative lesion and mucosal abrasion in the sigmoid colon. On pathology amyloid deposits were noted in the wall of a submucosal vessel. The amyloid deposits were localized in the large intestine. This patient likely had localized primary AL-type amyloidosis. The patient's symptoms quickly improved with intravenous hypernutrition.
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© 2009 Japan Gastroenterological Endoscopy Society
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