Abstract
A case of synchronous triple cancers of the esophagus, stomach, and duodenum is reported. The patient was a 73 years old man. Gastrointestinal endoscopy and computed tomography revealed triple advanced cancers : an esophageal cancer involving left main bronchus, a gastric cancer and a duodenal cancer. The esophageal cancer was thought to be unresectable, and we planned to perform chemotherapy. We thought the most fatal cancer was the escophageal cancer and performed chemotherapy using the protocol at first selected for unresectable esophageal cancer : CDDP 80mg/m2+5FU 800mg/m2 once a month. At the second course of chemotherapy, CDDP was reduced to 40mg/m2 because of renal dysfunction. After the third course of chemotherapy, the esophageal cancer was partially remitted and the gastric cancer was completely remitted, but the duodenal cancer was stable. Two months after the third course of chemotherapy, esophago-mediastinal fistula occurred and esophageal metallic covered stent was placed into the esophagus. The esophago-mediastinal fistula was covered by the stent, and the stent relieved the patient not only from fever and chest pain but from dysphagia. He seemed to have been comfortable until he died from progression of the cancer five months after the third course of chemotherapy.
