Abstract
A 64-year-old male endoscopic mucosal resection for a colonic adenoma had a follow-up colonoscopy. On colonoscopy, a whitish, slightly elevated lesion, 2mm in diameter, which had a smooth surface, was found in the descending colon. On histology, proliferation of ganglion cells and nerve fibers within the lamina propria was noted. On immunostaining, the lesion was positive for S-100 protein. The patient had no history of von Recklinghausen's disease or multiple endocrine neoplasia. Ganglioneuroma occurring only in the colon is very rare. Of note, this patient had the smallest colonic ganglioneuroma reported in the literutune to date.
