Abstract
A 61-year-old female was diagnosed as an unresectable advanced esophageal cancer with hepatic and lymph node metastases. Firstly, CDDP (70mg/m2/day, day 1)/5-FU (700mg/m2/day, days 1-4) combination therapy was given every four weeks for a total of five courses. After chemotherapy, both the hepatic and lymph nodes metastases could not be detected on computed tomography. Next, 60Gy-radiation therapy was given for residual esophageal cancer in the mid esophagus. Diagnostic testing confirmed the disappearance of the residual cancer. After six months, a IIb recurrent esophageal cancer was detected in the mid esophagus on diagnostic imaging. The tumor was resected en bloc using endoscopic submucosal dissection (ESD). No complication was noted. On histpathology, the resected tumor was an intraepithelial esophageal cancer. Both the lateral and vertical margins were negative. There was no recurrence for six months after ESD. In this paper, we report this case together with a review of the literature.