GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
SALVAGE ENDOSCOPIC SUBMUCOSAL DISSECTION FOR RECURRENT SUPERFICIAL ESOPHAGEAL CANCER OCCURRING AFTER CHEMOTHERAPY AND RADIATION THERAPY
Naoki ISHIINoriyuki HORIKIShino UCHIDAShoko SUZUKIMasayo UEMURAYusuke IIZUKAKatsuyuki FUKUDAYoshiyuki FUJITASeiji OHIGASHIKoyu SUZUKIToshiyuki ITOH
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JOURNAL OPEN ACCESS

2009 Volume 51 Issue 9 Pages 2431-2436

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Abstract
A 61-year-old female was diagnosed as an unresectable advanced esophageal cancer with hepatic and lymph node metastases. Firstly, CDDP (70mg/m2/day, day 1)/5-FU (700mg/m2/day, days 1-4) combination therapy was given every four weeks for a total of five courses. After chemotherapy, both the hepatic and lymph nodes metastases could not be detected on computed tomography. Next, 60Gy-radiation therapy was given for residual esophageal cancer in the mid esophagus. Diagnostic testing confirmed the disappearance of the residual cancer. After six months, a IIb recurrent esophageal cancer was detected in the mid esophagus on diagnostic imaging. The tumor was resected en bloc using endoscopic submucosal dissection (ESD). No complication was noted. On histpathology, the resected tumor was an intraepithelial esophageal cancer. Both the lateral and vertical margins were negative. There was no recurrence for six months after ESD. In this paper, we report this case together with a review of the literature.
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© 2009 Japan Gastroenterological Endoscopy Society
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