2010 Volume 52 Issue 5 Pages 1403-1407
A 75-year-old man was admitted to our hospital with epigastralgia and hematemesis. Endoscopy revealed a huge submucosal hematoma in the antrum of the stomach, which was the source of the bleeding. The hematoma ruptured, leading to the formation of an ulcer. Since gastric mucosal biopsy revealed amyloid deposition, and IgA-κ-type M protein was detected in the serum, the patient was diagnosed as having AL amyloidosis due to multiple myeloma. We were able to endoscopically observe the submucosal hematoma transform into an ulcer.