Abstract
We report on a case of a 44-year-old man presenting with a positive fecal occult blood test. A barium enema study showed a long pedunculated polyp, 50 mm in length, in the descending colon. An endoscopic examination showed the polyp had normal mucosa. Unevenness and swelling was observed at the head of the polyp. A colonoscopic polypectomy was performed. Histologically, the polyp was characterized by normal mucosa, and an edematous submucosal layer with dilated vessels and lymphatics, and there was no muscular layer. This polyp was diagnosed as a colonic muco-submucosal elongated polyp (CMSEP). We evaluated the case clinicopathologically and reviewed 59 cases of CMSEP in the Japanese literature.