TWO CASES OF SUPERFICIAL ESOPHAGEAL CANCER DIAGNOSED WITH THE METALLIC SILVER SIGN IN THE ESOPHAGUS SHOWINGMANY IODINE-UNSTAINED AREAS

Abstract

The metallic silver sign is the finding whereby a positive pink color sign (PC sign) area changes to silver with narrow band imaging (NBI) observation. Although it has been reported that the metallic silver sign is useful for diagnosis of superficial esophageal cancer especially in the esophagus, demonstrating many iodine-unstained areas because it stands out from the surround mucosa and is easy to detect, there are only a few studies on this application. We report two cases of superficial esophageal cancer which were detected with the metallic silver sign in the esophagus, showing many iodine-unstained areas, and treated with endoscopic submucosal dissection.