Abstract
We report herein on 3 patients with anal condyloma acuminatum identified following a biopsy of a bulging lesion that was found via retroflex visualization of the rectum. Anal condyloma acuminatum is closely associated with human immunodeficiency virus (HIV) infection and is often difficult to treat. In patients with this condition, magnified observation with narrow band imaging (NBI) revealed capillary blood vessels twisted like a hairpin on the surface of the mucus membrane. Such findings could be useful in differentiating anal condyloma acuminatum from other bulging lesions.