Abstract
We experienced a case of primary squamous cell carcinoma of the stomach. A 67-year-old man was admitted with epigastralgia. Endoscopic findings showed an ulcerative lesion on the lesser curvature of the gastric antrum. The tumor was diagnosed as squamous cell carcinoma from a biopsied specimen. An 18F-fluorodeoxyglucose positron emission tomography / computed tomography (FDG-PET/CT) study showed high FDG accumulation in the antrum of the stomach, and showed no malignancy at other sites. A distal gastrectomy with regional lymph nodes dissection was performed. Histopathological examination disclosed moderately or poorly differentiated squamous cell carcinoma without an adenocarcinoma component in all sections, and showed normal gastric mucosa between the squamous cell carcinoma of the stomach and the esophagus. Primary squamous cell carcinoma of the stomach is very rare. Only 45 cases, including our case, have been reported in Japan.