Abstract
This review introduces the methodology and characteristic findings of autofluorescence imaging (AFI). AFI is a simple procedure for identifying abnormal lesions as areas with a magenta color, thus making it possible to achieve an objective and reproducible diagnosis. Sufficient preparations, clear and enfaced images with the appropriate extension of the colon are important for making an accurate diagnosis of colon disorders with AFI. AFI is useful for discriminating colon neoplasia from non-neoplasia, evaluating dysplastic grades of colon adenoma and assessing the severity of ulcerative colitis. AFI thus provides important information for deciding on the necessity of endoscopic resection and the staging of lymphoma, and designing a therapeutic strategy for ulcerative colitis. AFI with a high-tracking and high-resolution system will be developed and is considered to be a powerful clinical option for making an endoscopic diagnosis.
