A CASE OF GASTROINTESTINAL STROMAL TUMOR ARISING FROM MECKEL'S DIVERTICULUM WITH GASTROINTESTINAL BLEEDING

Abstract

A 62-year-old woman was admitted to our hospital because of lower intestinal bleeding. The diagnosis of Meckel's diverticulum was made by small bowel imaging and transanal double-balloon enteroscopic examination. Partial resection of the ileum was performed. Pathological examination of the resected specimen showed proliferation of spindle-shaped cells in the wall of the diverticulum. The tumor was diagnosed as a gastrointestinal stromal tumor (GIST) by reason of immunohistochemical staining that was positive for c-kit and CD34 and negative for desmin and S-100. The coexistence of Meckel's diverticulum and GIST is considered to be rare. However, when Meckel's diverticulum is diagnosed, the possibility of the coexistence of neoplastic diseases should be kept in mind.