Abstract
Endoscopic submucosal dissection (ESD) for colorectal tumors has been conducted by the government-approved advance medical treatment system since August 2009. Then, in April 2012, the governmental public insurance system began to cover colorectal ESD. The present article described preparations, techniques and accident prevention for beginners in colorectal ESD. From the technical aspect, we gave detailed instructions on how to use the IT knife nano and dual knife. Important points in using the IT knife nano for colorectal ESD are maintaining a good visual field and avoiding blind operations. There is not a great difference between the IT knife nano and the tip-type knives. We have successfully performed colorectal ESD with a shortened procedure time while preserving quality and safety since the introduction of the IT knife nano. Beginners should decide which knife that they will mainly use and make an effort to master the techniques required for colorectal ESD.