2014 Volume 56 Issue 10 Pages 3607-3616
[Purpose] The purposes of this study were to evaluate the degree of awakening from sedation with propofol in patients who underwent upper esophagogastroduodenoscopy (EGD), and clarify the follow-up period required until the patient becomes able to leave the hospital safely. [Methods] The subjects were 104 patients who were sedated with propofol on EGD using the administration method established before this study. The evaluation items consisted of the mean blood pressure, arterial blood oxygen saturation, grip strength, visual acuity, Mini Mental State Examination (MMSE), and reflex nerve test. The results before examination were compared with those at 10 and 60 minutes after completion of the examination. [Results] There were significant decreases in the mean blood pressure, grip strength, and MMSE ten minutes after completion of examination. Although there was a significant decrease in blood pressure 60 minutes after completion of the examination, the value was higher than at 10 minutes. At 60 minutes, the grip strength and MMSE had returned to the pre-examination values. [Conclusion] EGD could be safely performed under sedation with propofol. Sixty minutes after completion of examination, items other than the mean blood pressure had returned to the pre-examination values. The blood pressure met the criterion for leaving the hospital. It may be possible to leave the hospital safely at 60 minutes after EGD.
