Abstract
Objective:This study compared the acceptance by patients of unsedated transnasal versus sedated peroral upper gastrointestinal endoscopy using pethidine hydrochloride.
Methods:A total of 274 patients who underwent both sedated peroral and unsedated transnasal endoscopy for screening purposes, were analyzed retrospectively. Acceptance by patients was assessed using a questionnaire completed by patients after each procedure and the number of occurrences of gagging reflex.
Results:Compared with the previous sedated peroral endoscopy, 77.4% (212/274) of patients stated that they tolerated unsedated transnasal endoscopy well. Among all patients, 72.3% (198/274) of patients stated that they were willing to undergo unsedated transnasal endoscopy in the future. The number of gagging episodes was significantly lower in unsedated transnasal endoscopy (p<0.05).
Conclusion:Transnasal upper gastrointestinal endoscopy is well tolerated and considerably reduces patient discomfort compared with sedated peroral endoscopy with pethidine hydrochloride.
