A RESECTED CASE OF PANCREATIC CANCER DIAGNOSED BY EUS-FNA, WHICH WAS USEFUL IN DIFFERENTIATION FROM PANCREATIC METASTASIS FROM LUNG CANCER

Abstract

A 76-year-old woman was diagnosed with pancreatic cancer by endoscopic ultrasonographic fine-needle aspiration (EUS-FNA) biopsy. She had undergone thoracoscopic left lower lobe resection for lung cancer 14 months before presenting to our department. Thyroid transcription factor-1 (TTF-1) was positive in the adenocarcinoma of the resected lung cancer. Since serum CYFRA and CEA levels, which were negative after the surgery, increased again, recurrence of the lung cancer was suspected. FDG-PET examination showed intense uptake in the pancreatic head, and therefore pancreatic metastasis of lung cancer was suspected. CT and MRI revealed no dilatation of the main pancreatic duct and a deeply stained, ring-like tumor ; therefore, these results also supported the diagnosis of pancreatic metastasis of lung cancer. EUS-FNA biopsy was performed, and TTF-1-negative adenocarcinoma was detected. The patient subsequently underwent pylorus-preserving pancreaticoduodenectomy.