SIGNET RING CELL CARCINOMA OF THE APPENDIX THAT WAS DIAGNOSED PREOPERATIVELY : A CASE REPORT

Abstract

An 80-year-old woman visited our hospital with a complaint of constipation. Colonoscopy revealed a submucosal tumor-like elevated lesion in the appendix orifice which had a depression in the center. A biopsy material taken from the epithelia of the appendix orifice revealed signet ring cell carcinoma, and ileocecal resection was carried out. Microscopically, most of the lesion was occupied by signet ring cells, but tub2 and muc coexisted in the same lesion. It is suggested that signet ring cell carcinoma had originated from tubular adenocarcinoma.