Abstract
A 50-year-old male with right lower abdominal pain consulted a nearby general practitioner, and was referred to the emergency room of our hospital with the suspicion of appendicitis. Abdominal CT revealed an intussusception, along with a large cecal lipoma that was thought to be the cause of the intussusception. Emergency colonoscopy then uncovered a submucosal tumor (SMT) that appeared to be the lead point of the intussusception, which was reduced endoscopically. Further, to prevent recurrence of intussusception, endoscopic unroofing (EU) was performed. This case suggests that, under the appropriate conditions, one-step EU can be an effective choice for reduction of an intussusception arising from a lipoma. We report its details along with a review of related literature.