2016 Volume 58 Issue 12 Pages 2412-2417
A 40-year-old man was referred to our hospital due to several episodes of vomiting after meals. Endoscopy revealed circular stenosis in the entire second portion of the duodenum (the length of the stenotic section was about 5cm), and biopsy specimens showed no malignant cells. Three months after gastrojejunal bypass operation, the gross appearance on endoscopy had changed little. However, examination of biopsy specimens revealed signet ring cell carcinoma in the lamina propria mucosae. He underwent surgical resection, and pathological findings revealed poorly differentiated adenocarcinoma with signet ring cells that showed a diffuse invasive pattern.