Abstract
[Background and Objective] The influence of differences in the shape of forceps on tissue preparations and histological diagnosis is unclear. These were investigated in atypical epithelial samples that were difficult to histologically distinguish as benign or malignant. [Subjects and Methods] Thirty-three and 29 samples of atypical epithelium biopsied using alligator or standard forceps, respectively, which were difficult to diagnose as benign or malignant were investigated. The quality of tissue preparations was investigated based on the area, crushing, and direction, and the influence on the diagnosis was studied by comparing the histological diagnosis of the samples and actual diagnosis of the patients during their observation course. [Results] The tissue area of the samples collected using alligator forceps was larger with less crushed tissue, the direction was retained, and the number of samples that were difficult to diagnose on the first histological examination was smaller. [Conclusion] The difference in the shape of biopsy forceps may influence the quality of tissue preparations and histological diagnosis.
