Abstract
We report the endoscopic and histopathological findings of a case of autoimmune gastritis with multiple polyp-like nodules in the lesser curvature, anterior wall, and posterior wall of the gastric body. The patient was a 41-year-old woman who was incidentally found to have multiple polyp-like, elevated lesions in the stomach during the annual medical check-up. Laboratory examination revealed iron deficiency anemia and marked hypergastrinemia. On endoscopic examination of the stomach, whereas the antral mucosa was well preserved, the fundic mucosa was markedly atrophic, and the remaining non-atrophic mucosa was seen as multiple, island-like, elevated areas. On histopathological examination of the biopsied gastric mucosa, chief cells and parietal cells were nearly absent in the atrophic areas. In the remaining non-atrophic areas of the fundic mucosa, lymphocytic infiltration in the lamina propria was prominent, and many lymphocytes were found to have surrounded and destroyed the oxyntic glands. The description of endoscopic findings of multiple protuberances in the lesser curvature, in which active lymphocytic infiltration was prominent around the oxyntic glands, has been reported only rarely.
