2017 Volume 59 Issue 1 Pages 48-55
A 57-year-old man presented to our hospital with a chief complaint of diarrhea. Colonoscopic examination revealed a submucosal tumor of 3 cm in diameter appearing as a nodular elevation on the posterior wall of the lower part of the rectum (Rb). Endoscopic ultrasonography (EUS) demonstrated a lesion composed of multiple cysts located in the submucosa. A biopsy and EUS-guided fine needle aspiration (FNA) failed to yield findings allowing a definitive diagnosis to be made. In order to establish a diagnosis and devise the optimal treatment, the lesion was transanally resected and examined histopathologically. This confirmed the diagnosis of colitis cystica profunda (CCP). This disease is also subclassified as a gross morphologic type of rectal mucosal prolapse syndrome, but the frequency of CCP is rare. We herein discuss the clinical features of this uncommon disease with a review of the relevant literature.