2018 Volume 60 Issue 1 Pages 5-13
Early gastric cancer discovered after Helicobacter pylori eradication therapy (EGCAE) is generated from gastric mucosa that had been infected with H. pylori, and was subsequently modified by the eradication therapy. A reddish depressed lesion is a typical endoscopic feature of differentiated type EGCAE. Histological examination reveals epithelium with low-grade atypia that covers the tumor tissue. Consequently, it is difficult to detect EGCAE endoscopically, and some lesions are discovered later as cancers with submucosal invasion. It is important for endoscopists to be able to recognize EGCAE so that treatments can be administered at the early stage of cancer. Endoscopists should be aware of the characteristic features of EGCAE.
