2018 Volume 60 Issue 12 Pages 2499-2504
A 75-year-old man underwent screening upper gastrointestinal endoscopy, which detected a submucosal tumor measuring 2 cm in the angulus on the lesser curvature side. His condition was monitored by periodic endoscopy, but the tumor showed a growth tendency in the sixth year of monitoring. In the seventh year, mucosal cutting biopsy led to the diagnosis of solid-type poorly differentiated adenocarcinoma. Epstein-Barr virus (EBV) was detected and the preoperative diagnosis was gastric carcinoma with lymphoid stroma (GCLS). Based on these findings, we performed total gastrectomy. This case is considered to be valuable in that it allowed us to follow the natural course of GCLS, and we therefore report our experience.
