2018 Volume 60 Issue 4 Pages 1003-1009
An 82-year-old male was admitted to our hospital because of lower digestive tract bleeding. After previous surgical operation for spinal canal stenosis, diclofenac sodium was administered for many years due to low back pain. On lower digestive tract endoscopy, a diaphragm-like stricture was observed in the vicinity of the transverse colon-splenic flexure area, and an ordinary endoscope could not be passed through the stricture. For this reason, a nasogastric endoscope was used and the cecum was observed. Multiple ulcerative lesions and 11 diaphragm-like strictures were observed from the ileocecal region to the transverse colon. Disease-specific findings were not observed in biopsy specimens nor in tissue culture. Laparoscopic-assisted enlarged right hemicolectomy was performed to excise the portion of the colon with strictures. The diagnosis of nonsteroidal anti-inflammatory drug (NSAID)-induced colonic lesions was made. There are few reported cases of NSAIDs-induced diaphragm-like colonic stricture. We report this case including histological findings.
