A CASE OF RIGHT-SIDED COLITIS SHOWING COBBLESTONE-LIKE APPEARANCE AND MULTIPLE ULCERS IN A PATIENT WITH FAMILIAL MEDITERRANEAN FEVER

Abstract

We report a rare case of right-sided colitis showing cobblestone-like appearance and multiple shallow ulcers associated with familial Mediterranean fever. A 60-year-old man presented with a recent history of several episodes of high fever, abdominal pain and diarrhea. Gene analysis showed variations of the MEFV gene in the exon 3 and exon 8 splicing donor sites. Oral administration of colchicine was effective for relief of his signs and symptoms and improvement of colitis as demonstrated by colonoscopy. He had two gastric ulcer scars in the gastric antrum with gastric fundic polyps, and the healed colonic mucosa was covered with intestinal spirochetes.