2020 Volume 62 Issue 9 Pages 1600-1606
We report a case of anaplastic pancreatic cancer showing osteoclast-like giant cells, which was preoperatively diagnosed using endoscopic ultrasound (EUS)- fine needle aspiration (FNA). A 68-year-old woman underwent contrast-enhanced computed tomography (CT) for evaluation of recurrent acute pancreatitis. CT revealed a hypovascular tumor involving the head of the pancreas. EUS revealed a hypoechoic mass (12×11mm) in the head of the pancreas, and EUS-FNA performed for further evaluation revealed dysplastic cells suspicious for malignancy in addition to osteoclastic giant cells. Therefore, the patient was diagnosed with anaplastic pancreatic cancer with osteoclast-like giant cells. She underwent pancreatoduodenectomy, and the resected tumor (13×12mm in size) is the smallest pancreatic tumor recorded in the Japanese literature. The tumor was classified as TS1 according to the Japanese classification system of pancreatic cancers. The patient received postoperative S-1 adjuvant chemotherapy for six months, and she continues to do well without recurrence, 4 years and 9 months postoperatively.
