2023 Volume 65 Issue 12 Pages 2394-2400
A Japanese man in his twenties was diagnosed with esophageal tumor. However, the tumor was not further investigated at the time of diagnosis. At 73 years of age, he was diagnosed with esophageal leiomyoma with calcification after undergoing EGD and boring biopsy. Subsequently, he defaulted follow-up. At 75 years, he was referred to our hospital due to persistent postprandial vomiting. EGD revealed a yellowish-white, hard, rough-surfaced, 30 mm mass covered with normal mucosa in the lower thoracic esophagus. As a result of insufflation during this procedure, the mass detached and fell into the lumen of the esophagus. Because it appeared to be obstructing the esophagus, various endoscopic procedures to shrink the mass were repeatedly performed, culminating in crushing and removal from the stomach by electrohydraulic lithotripsy. Histopathological diagnosis of the retrieved specimen was calcified leiomyoma. Electron microscopic and infrared spectroscopic analyses revealed that the calcified component was carbonate apatite. To the best of our knowledge, this is the first report of a patient with a calcified esophageal leiomyoma that detached and fell into the lumen of the esophagus.