2023 Volume 65 Issue 5 Pages 448-453
A 42-year-old woman visited our hospital for anemia and multiple polyps in her stomach. Endoscopy revealed a dense growth of sessile to sub-stemmed polyps throughout her stomach and elevated lesion caused by polyp aggregation in the gastric antrum. We initially decided to observe the patient for anemia caused by multiple gastric hyperplastic polyps, but ultimately decided to perform total gastrectomy because the elevated lesion in the gastric vestibule expanded over time, and a biopsy suggested adenocarcinoma. The pathological diagnosis was juvenile polyposis syndrome complicated by early gastric carcinoma. Stomach-limited juvenile polyposis syndrome with anemia and hypoalbuminemia tends to develop into gastric cancer. However, diagnosing comorbid cancer is often difficult, so prophylactic total gastrectomy should be considered in such cases.
