2024 Volume 66 Issue 11 Pages 2577-2584
A 50-year-old woman with a 2-year history of bronchial asthma presented with abdominal pain and diarrhea, followed by purpura and painful hypesthesia in the lower extremities and limb weakness. Laboratory data showed markedly increased eosinophils in peripheral blood. Eosinophilic gastroenteritis was suspected; therefore, a CS was performed that revealed multiple irregular erosions, shallow ulcers, and redness of the surrounding mucosa throughout the terminal ileum and colon. During CS, a polyp containing mild inflammatory changes in the sigmoid colon was identified and removed via EMR. Pathological findings included numerous eosinophilic infiltrations and granulomatous vasculitis. Based on the clinical findings, eosinophilic granulomatosis with polyangiitis was diagnosed according to the criteria of the Ministry of Health, Labor and Welfare. The diagnosis was confirmed by histological evaluation of the submucosa in the EMR specimen, which also contained a coexisting colorectal adenoma.
