2024 Volume 66 Issue 2 Pages 157-162
A 64-year-old man with a complaint of loose stools was found to have accumulation of white fluid in the duodenum at the time of EGD. Duodenal biopsies were performed, and histopathological examination revealed sickle-shaped and pear-shaped bodies on the mucosal surface, suggesting Giardia intestinalis. The patient was diagnosed with assemblage A-type G. intestinalis by microscopic examination and PCR-sequencing of duodenal fluid and stool samples. The patient was treated with metronidazole 750 mg/day for 7 days to deworm. After the treatment, the patientʼs stool returned to normal. One year later, EGD was performed, and white fluid accumulation was not observed in the duodenum. G. intestinalis was not detected by microscopic examination of stool samples, duodenal fluid, and duodenal biopsies; hence, it appeared that deworming was successful. G. intestinalis infection should be considered when white fluid accumulation is observed in the duodenum during EGD.