2024 Volume 66 Issue 3 Pages 229-242
Japan Gastroenterological Endoscopy Society (JGES) guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment is compared with the Endoscopy-related Societies Worldwide guidelines. The JGES guidelines focus on reducing the risk of thromboembolism occurrence, particularly in the treatment of DOAC withdrawal and resumptive periods. Many aspects with unclear evidences remain, and further investigation is required. Issues that should be resolved eventually include the positioning of cold polypectomy, whether endoscopic treatment is possible under continued P2Y12 antagonists, positioning of heparin replacement in alternative treatment for DOAC withdrawal, and temporary replacement of DOAC for warfarin withdrawal.