2024 Volume 66 Issue 4 Pages 417-421
PureStatⓇ, a self-assembling peptide solution, has been approved and marketed in Japan as a hemostatic agent for gastrointestinal endoscopy. We report a case of a 60-year-old man who was successfully treated for bleeding with PureStatⓇ after colorectal EMR, in which the bleeding point was difficult to identify. He was referred to our hospital after a colonoscopy at his previous hospital revealed an elevated lesion in the sigmoid colon. After EMR for a 15-mm type-Ⅰsp colorectal tumor in the sigmoid colon, there was pulsatile bleeding from the wound. The wound was sutured with multiple clips, but the bleeding persisted through the gap between the clips. Because a series of clips were already attached to the wound, additional clips could not be applied. In addition, coagulation and hemostasis with hemostatic forceps were difficult due to the inability to identify the bleeding point. Therefore, hemostasis was performed using PureStatⓇ. This case suggests that the application of PureStatⓇ may be a safer treatment option for post-EMR hemorrhage patients whose bleeding cannot be controlled by clipping alone.