CLINICAL APPLICATION OF PERORAL ENDOSCOPIC TUMOR RESECTION FOR SUBEPITHELIAL LESIONS IN THE ESOPHAGUS AND ESOPHAGOGASTRIC JUNCTION

Abstract

Peroral endoscopic myotomy (POEM) has become the standard treatment for achalasia, especially because it allows access to deeper layers beyond the submucosal layer that were previously accessible only through surgical procedures. As a result, ʼsubmucosal endoscopyʼ has emerged as a novel diagnostic and therapeutic strategy in therapeutic endoscopy. Submucosal endoscopy is a comprehensive concept that includes endoscopic techniques facilitating safe access to the submucosal and muscle layers as well as deeper cavities. One technique performed endoscopically within the submucosal tunnel is peroral endoscopic tumor resection (POET), which involves the endoscopic removal of subepithelial lesions. This article provides a detailed overview of the indications and practical aspects of POET.