2025 Volume 67 Issue 10 Pages 1523-1534
Although obesity treatment primarily targets the gastrointestinal tract, the opportunities for endoscopists in Japan to be involved in obesity management are limited. Recently, various endoscopic bariatric and metabolic therapies (EBMTs) have been developed to overcome the limitations of conventional medical and surgical treatments. Among them, endoscopic sleeve gastroplasty is gaining global recognition as a reliable obesity treatment because of its minimally invasive nature compared to surgery and superior weight loss efficacy compared to pharmacotherapy. This review outlines the current trends in EBMTs that endoscopists should note, in the context of recently approved glucagon-like peptide-1 receptor agonists for obesity treatment.