2025 Volume 67 Issue 10 Pages 1569-1575
A 63-year-old man with suspected acute pancreatitis was admitted to our hospital. Computed tomography revealed a mediastinal pancreatic pseudocyst with a background of chronic pancreatitis. Pancreatography showed extraductal leakage of contrast medium into the cyst, leading to the diagnosis. After endoscopic nasopancreatic drainage, the mediastinal pancreatic pseudocyst shrank; therefore, a pancreatic duct stent was placed. Multiple pancreatic duct stent exchanges were performed to achieve spontaneous closure of the pancreatic duct collapse and stent removal. Here, we report the usefulness of endoscopic treatment of mediastinal pancreatic pseudocysts and discuss the literature.