2025 Volume 67 Issue 10 Pages 1605-1688
The Japanese Association for Capsule Endoscopy has developed the “Clinical Practice Guidelines for Capsule Endoscopy” according to evidence-based medicine, following the “Minds Manual for Guideline Development 2020 ver. 3.0.” Capsule endoscopy (CE) enables minimally invasive examination of the digestive tract lumen. In Japan, CE for the small intestine has been covered by national health insurance since 2007. Reimbursement for CE of the colorectum in Japan was approved in 2014. Currently, CE is indicated for the small intestine and colorectum. These guidelines consist of clinical questions (CQs), background questions (BQs), and future research questions (FRQs). Some CQs are based on expert consensus due to limited high-level evidence.
These guidelines provide clinical guidance on the use of small intestine CE, colon CE, unapproved CE, patency capsule, endoscopic capsule delivery, reading supports, and CE in out-of-clinic settings.