2025 Volume 67 Issue 12 Pages 2422-2427
A 73-year-old woman diagnosed with hepatitis C virus-related liver cirrhosis who had been receiving antiviral therapy for the previous 10 years was referred to our hospital for gastric cancer treatment. EGD revealed a well-demarcated superficial depressed lesion and nodular gastric varices (GV) on the body and fundus of the stomach, respectively. Lesion biopsy revealed well-differentiated adenocarcinoma. Endoscopically, the lesion was diagnosed as early gastric cancer localized within the mucosa and suitable for ESD. Prior to ESD, balloon-occluded retrograde transvenous obliteration (BRTO) of the GV was performed to prevent variceal bleeding. The lesion was successfully resected 2 months after BRTO with no remarkable complications or variceal bleeding. BRTO prior to ESD for gastric cancer was safe and effective for the prophylaxis against GV bleeding, and no difficulties were encountered during ESD.