2026 Volume 68 Issue 2 Pages 119-126
Objective: This study aimed to prospectively evaluate the efficacy of bowel preparation with PEG-Asc monotherapy for CS and identify factors associated with prolonged preparation time.
Methods: In total, 237 patients (mean age, 64.2 years; male-to-female ratio, 151:86) were enrolled. Laxatives were not administered, and all patients consumed a diet meal the day before the CS. The preparation was performed using the 2:1 method, in which the patients drink two cups of PEG-Asc and one cup of water or tea on the day of CS. The efficacy, safety, and factors that prolonged the preparation time were examined.
Results: The mean volume of PEG-Asc consumed was 1,474 mL, and the mean preparation time was 189.6 min. Adequate bowel cleansing was achieved in 99.2% of patients, and no severe adverse events were observed. According to multivariate analysis, the factors that prolonged the preparation time to more than 180 min were age over 65 years and no defecation on the day before and morning of the CS. The preparation time was significantly shorter if the patients defecated on the day before and on the morning of the CS, even if the amount was small.
Conclusions: This method is safe and effective for CS. Our results suggest that laxatives for adjuvant use are not necessary for patients who defecate the day before or on the morning of CS.
