Abstract
A 64 year old male presenting with epigastric pain was seen at the Aichi Cancer Center Hospital in June 1969. Upper gastrointestinal series revealed a IIa+IIc like lesion on the posterior wall of the distal antrum. Endoscopically, the lesion appeard an early gastric cancer of IIa+IIc type. However, gastric biopsy done at that time was interpreted as gastritis. The third biopsy examination done in November 1972 demonstrated atypical epithelium and the lesion had since been followed up as a border-line lesion until the eighth biopsy in May, 1973 raised a suspicion of gastric cancer (interpreted as group IV). The endoscopic appearance of the lesion seen as ha +IIc type early gastric cancer had not been changed during the follow-up period. A Billroth I gastric resection was performed and the resected specimen demonstrated a IIc like depressed lesion, 25 x 30mm in size, on the posterior wall of the natrum. Histologically, the lesion represented a slight depression covered by atypical epithelium. Atypical epithelium of depressed type has been rarely reported and simulates an early gastric cacer of IIc type in gross appearance.