Abstract
The dyeing of the colonic mucosa with indigocarmine or methylene blue solution was performed in 80 patients during colonofiberscopy.1. The superficial changes of the normal colonic mucosa on dyeing showed a regular, fine foldlike or granularappearance.2. In the early stage or in the stage of remission of chronic ulcerative colitis, the mucosal changes were classified into the following 3 patterns;1) the spotted appearance2) the hazy appearance3) the cobblestone appearanceThe classification was useful to indicate the degree of regeneration of the colonic mucosa.3. The dyeing gave much information on finding the border area between the normal and the abnormal.4. The mucosal changes of the colon were demonstrated characteristically in the case with tuberculosis or non-specific ulcer of the intestine.5. In polyp or polyposis of the colon, the superficial min-ute changes were observed. The dyeing was useful to determine the indication for endoscopic polypectomy, to identify the location of the polyp accurately although the differentiation benign polyp and polypoid carcinoma was not always possible.6. Inflammatory pseudopolyposis and lymph follicles which were not dyed were better observed with the surrounding mucosa completely dyed. The dye spray method was highly effective in the de-monstration of the superficial minute changes of the colon in both the ulcerous and the protruded lesions.
