Abstract
Gastric ulcers have been thought to occur only in the pyloric gland area. However, endoscopic examinations, using the Congo red test, revealed that 18 ulcers (7.8%) were surrounded by an acid-secreting area and so were, in the fundic gland area. Histological examination of specimens obtained by gastrectomy also showed that 5 lesions (4.4%) were localized in the fundic gland area. Ulcers in the f undic gland area occurred most frequently in the angle and lower gastric body, adjacent to the acid secreting boundary. These ulcers were associated with little or no fundal gastritis, while ulcers in the pyloric gland area were usually associated with moderate or severe fundal gastritis. Repair of ulcers surrounded by normal fundic mucosa was complete although these ulcers were similar in depth to ulcers located in the pyloric gland area. No recurrence of these ulcers was seen in a 1-year endoscopic follow-up period.
