Abstract
"Colitis aphtosa", which was first reported by Yoshikawa (1973), is considered to be a new entity of inflammatory colon disease. Its clinical and laboratory findings, especially its endoscopical findings, are different from other specificand non-specific inflammatory colon diseases. Multiple small round erosions, found at the lymphapparatus in the mucosa or the submucosa, is distinguished from other inflammatory colon diseases. Its etiology is, however, not elucidated yet. Recently, we have experienced a case of familiar onset of "colitis aphosa" whic is interest to suggest the etiogy of this disease. A thirty-six year old man was admitted to our hospital, complaining of abdominal pain, slight fever, sence of fullness and anal bleeding. Clinical examinations showed leukocytosis (12100/mm3) and occult blood positive, but no significant bacillus or virus was found out. Endoscopical examination, using colonof iberscope type CF-MB-M (Olympus), revealed multiple small round redness and/or erosion in the rectum. Immediately, colonofiberscopic examination was carried out to his family, and his father (69 year old) and his wife (34 year old) who were boarding with him had similar findings on the rectal mucosa, and they were diagnosed "colitis aphtosa." However, his daughter (9 year old) and son (6 year old) who were boarding with, and his two sisters (47 year old, 42 year old) and one brother (34 year old) who were not boarding with, and his two sisters (47 year old, 42 year old) and one brother (34 year old) who were not boarding with had no positive findings. Therefore, it cann of completely rule out that the etiology of this disease has a posibility of a certain inf ecious disease.
