Abstract
The authors reported the actual incidence of upper gastrointestinal disease following CNS injuries was about 70 % by endoscopic observation. In the present study, natural history of acute upper gastrointestinal disease after CNS injuries was performed in 33 cases.1) None of hemorrhagic erosion developed into acute gastric ulcer. However, in two cases, an ulcer was observed to evolve from an duodenal erosion.2) Although the healing was protracted in some cases, acute gastric lesions usually healed in a few weeks.3) The course of gastroduodenal lesions did not parallel in the clinical status of the patients.4) The behavior of these upper gastrointestinal lesions was influenced by sepsis and hypotension.5) Administration of glucocorticoid had no relationship with the occurence and course of the stress ulcer.
