GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
DIAGNOSTIC APPROACH TO INTRAHEPATIC LESIONS BY EPCG REPORT 2
-DEMONSTRATION OF THE INTRAHEPATIC BILE DUCTS BY PHARMACOLOGICAL EPCG WITH INJECTION OF MORPHINE-
SET TOMATSUITARU OIFUMITAKE TOKIYUTAKA OBATATADAYOSHI TAKEMOTO
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1978 Volume 20 Issue 1 Pages 20-25_1

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Abstract
1t is not always easy to have complete visualization of the intrahepatic bile ducts of the cases which have normal gallbladders and biliary ducts by EPCG. We have developed ‘Pharmacological EPCG’ with Caerulein or CCK-PZ which showed better visualization than present EPCG. Now, we have developed and investigated Pharmacological EPCG' with morphine, which makes Sphincter of Oddi contract tightly and prevents the contrast medium injected by EPCG from flowing back out of the orifice of the duodenal papilla and demonstrates complete visualization of the intrahepatic bile ducts. We have compared three groups of the visualized intrahepatic bile duct branches. The groups are: (1) 15 cases with injection of morphine, (2)18 cases with injection of Caerulein or CCK-PZ and (3)45 cases without any injection. All cases have normal gallbladders and biliary ducts. The result: the best visualization of the intrahepatic bile duct branches was obtained in group (1)(injection of morphine), the second-best visualization in group (2)(injection of Caerulein or CCK-PZ). The poorest visuali-zation in group (3) (without any injection). However, I should point out that one patient in a group (1)developed acute pancreatitis.
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