Abstract
Peritoneoscopy and liver biopsy were carried out in 259 patients suffering from various liver diseases. Forty-four cases were acute hepatitis, 17lcases were chronic hepatitis, (inactive form 28, active form 122 and active form with bridging formation 21), and 44 cases were hepatic cirrhosis. The histological features were compared with macroscopic findings of peritoneoscopy and laboratory data including S-GOT, serum albumin, serum γ-globulin, cholinesterase, ICG disappearance rate, and 45 min BSP retention rate. Kalk's classification and Shimada's code criteria were employed for evaluation of the macroscopic findings. In the group of enlarged white liver, serum γ-globulin level and BSP retention rate were valuable to differentiate between acute hepatitis and chronic hepatitis. In the group of patchy nodular liver and early nodular liver, ICG disappearance rate appeared to correlate well with the existence of bridging formation which means clinically to be at the precirrhotic stage. Since the peritoneoscopic examination and liver biopsy were not always performed in all patients with liver diseases, predication from the laboratory data alone was required in such cases. Therefore, a scoring method using S-GOT, serum albumin, serum γ-globulin, ICG and BSP was designed. This method revealed that chronic active and inactive forms of hepatitis were able to differentiate each other clearly. In addition, we found that incidence of rheumatoid factor and HB, Ag in chronic active form were more frequent than in inactive one.
