Abstract
Intestinal metaplasia of the stomach under the age of 30 was studied endoscopically by vita staining of direct dye scattering method (0.5% methylene blue). The biopsy specimens were investigated under dissecting microscopic observation by double staining of LAP Leucine aminopeptidase) and AL-P (Alkaline phosphatase) according to the method of of 114 patients Nakahara. Following results were obtained; 1) Intestinal mataplasia was present in 8 of 36 patients (22%) of Second decade and 39 (34%) of third decade. 2) In 2 of 4 patients under the age of 30 followed up by endoscopy scanty methylene blue stained areas were seen in regenerating mucosa of gastric erosion, which were confirmed by histochemical investigation. The early stage of intestinal metaplasia of the gastric mucosa was seen in regenerating mucosa of eroded verrucous lesions or multiple erosions, and f ilamentous patterns were demonserated by using Olympus GIF-D3 with 8 magnification. 3) In cases without erosion in the stomach we experienced linear and ramified types of intestinalized mucosa at the initial stage.
