Abstract
A case of acute fulminating ulcerative colitis is reported, which show specific double contrast radiografic findings and colonoscopic picture. It was difficult to differ the case from drug induced colitis. In this case, serum immunoglobulin (IgG, IgA) level transiently increased and then return to normal level, following clinical remission. And in this case, steroid enema was more effective than steroid one shot infusion in mesenteric artery.